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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGFB3 All Species: 36.36
Human Site: T395 Identified Species: 88.89
UniProt: P10600 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10600 NP_003230.1 412 47328 T395 I L Y Y V G R T P K V E Q L S
Chimpanzee Pan troglodytes XP_001161571 412 47357 T395 I L Y Y V G R T P K V E Q L S
Rhesus Macaque Macaca mulatta XP_001100053 412 47296 T395 I L Y Y V G R T P K V E Q L S
Dog Lupus familis XP_854119 412 47164 T395 I L Y Y V G R T P K V E Q L S
Cat Felis silvestris
Mouse Mus musculus P17125 410 46866 T393 I L Y Y V G R T P K V E Q L S
Rat Rattus norvegicus Q07258 412 47097 T395 I L Y Y V G R T P K V E Q L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506409 334 38141 T317 I L Y Y V G R T P K V E Q L S
Chicken Gallus gallus P16047 412 47059 T395 I L Y Y V G R T P K V E Q L S
Frog Xenopus laevis P17247 413 47621 K396 I L Y Y I G N K P K I E Q L S
Zebra Danio Brachydanio rerio NP_919367 410 46964 T393 I L Y Y V G R T P K V E Q L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 99.7 98 N.A. 97 97.8 N.A. 71.5 87.3 53.7 73.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 100 99.2 N.A. 98.3 99 N.A. 75.2 93.6 70.6 85.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 73.3 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 86.6 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 100 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 100 0 0 0 0 0 % K
% Leu: 0 100 0 0 0 0 0 0 0 0 0 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % S
% Thr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 90 0 0 0 0 0 90 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 100 100 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _